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Tc1 cells are a specialized subset of CD8+ cytotoxic T lymphocytes (CTLs) that exhibit a Type 1 immune response profile, functionally analogous to Th1 (Type 1 helper) cells but in the cytotoxic lineage. These cells are polarized by specific cytokines during activation and are characterized by their production of Interferon Type II (IFN Type II) / Interferon Gamma (IFN-g), Tumor Necrosis Factor alfa (TNF-alfa), and interleukin-2 (IL-2), while typically not producing [Interleukin-4 (IL-4)](brain://oP9LSEBc…