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The randomized, double-blind treatment trial NCT02299973 - Fecal Microbiota Transplantation (FMT) (own stool) vs Fecal Microbiota Transplantation (FMT) (healthy donor stool) & Diarrhea-predominant Irritable Bowel Syndrome (IBS) (IBS-D)
revealed that Fecal Microbiota Transplantation (FMT) (healthy donor stool) alleviates symptoms more effectively than a placebo, which was an autologous transplant. However, the beneficial effects of FMT diminished over the course of a year. When a second FMT was administered, it successfully restored the response in patients who had previously responded to the treatment. The response to FMT was lin…