NCT03420482 - Fecal Microbiota Transplant (FMT) & Hepatic encephalopathy (HE)

Background:

Fecal microbiota transplant (FMT) shows early promise in treating hepatic encephalopathy (HE). The ideal characteristics for both FMT donors and recipients remain unidentified (1)

Study overview:

NCT03420482 - Fecal Microbiota Transplant (FMT) & Hepatic encephalopathy (HE) is a randomized clinical phase II treatment trial studying Fecal Microbiota Transplant (FMT) (oral capsules) or placebo in patients with Hepatic encephalopathy (HE) (1)

Primary outcome measures:

Psychometric Hepatic Encephalopathy Score (PHES)

Results:

After administering three doses of FMT, there was an improvement in the PHES by an average of 2.1 points, with a significance level of …