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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Nicotinic acetylcholine receptor inhibitors

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Nicotinic acetylcholine receptor inhibitors are a diverse group of compounds that block or reduce the activity of Nicotinic acetylcholine receptor

Snake and snail venoms contain potent Nicotinic acetylcholine receptor inhibitors, such as alfa-conotoxins from cone snails
Teichert et al. 2004 Toxicon 44(2): 207-14
Dutertre et al. 2017 Neuropharmacology 127: 196-223

Plant-derived compounds such as Ibogaine, found in Tabernanthe iboga, has been investigated for its potential in treating substance use disorders
Straub et al. 2023 J Med Chem. 66(1): 107-121

Synthetic compounds belong to mesoionic inse…

References (Sources)

AlphaA-Conotoxin OIVA defines a new alphaA-conotoxin subfamily of nicotinic acetylcholine receptor inhibitors
Teichert et al. 2004 Toxicon 44(2): 207-14
Mutschler Arzneimittelwirkungen
Geisslinger et al. 2020 Wissenschaftliche Verlagsgesellschaft mbH ISBN 978-3-8047-3663-4
Nicotinic acetylcholine receptor inhibitors derived from snake and snail venoms
Dutertre et al. 2017 Neuropharmacology 127: 196-223
Review
Recent Research Progress in and Perspectives of Mesoionic Insecticides: Nicotinic Acetylcholine Receptor Inhibitors
Liu et al. 2020v J Agric Food Chem. 68(40): 11039-11053
Review
What We Have Gained from Ibogaine: α3β4 Nicotinic Acetylcholine Receptor Inhibitors as Treatments for Substance Use Disorders
Straub et al. 2023 J Med Chem. 66(1): 107-121
Review

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Nicotinic acetylcholine receptor inhibitors

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