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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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AuthorsReferences (Sources)

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Fibroblast growth factor 10 (FGF10)

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Contents

Fibroblast Growth Factor-10 (FGF-10) is a member of the fibroblast growth factor family. It plays a significant role in the proliferation, differentiation, and migration of epithelial cells, particularly keratinocytes.

It has been investigated for its potential therapeutic benefits in several conditions:

Skin Protection (Gao et al. 2021 Front Pharmacol. 12: 655281)

Lung Injury (Fang et al. 2012 European Respiratory Journal 40: 4637; Bi et al. 2014 J Cell Mol Med. 18(6): 1226-35; Fang et al. 2014 Am J Respir Cell Mol Biol. 50(6): 1156-65)

Gastrointestinal Disorders (Sandborn et al. 2003 Aliment Pharmacol …

References (Sources)

Effects of keratinocyte growth factor-2 on corneal epithelial wound healing in a rabbit model of carbon dioxide laser injury
Wang et al. 2010 Biol Pharm Bull. 33(6): 971-6
Keratinocyte Growth Factor 2 Ameliorates UVB-Induced Skin Damage via Activating the AhR/Nrf2 Signaling Pathway
Gao et al. 2021b Front Pharmacol. 12: 655281
Keratinocyte growth factor-2 and autologous serum potentiate the regenerative effect of mesenchymal stem cells in cornea damage in rats
Pınarlı et al. 2014 Int J Ophthalmol. 7(2): 211-9
Keratinocyte growth factor-2 intratracheal instillation significantly attenuates ventilator-induced lung injury in rats
Bi et al. 2014 J Cell Mol Med. 18(6): 1226-35
Protective effects of keratinocyte growth factor-2 on ischemia-reperfusion-induced lung injury in rats
Fang et al. 2014 Am J Respir Cell Mol Biol. 50(6): 1156-65
Protective effects of keratinocyte growth factor-2 on warm ischemia reperfusion lung injury in rats
Fang et al. 2012 European Respiratory Journal 40: 4637
Therapeutic efficacy of a mutant of keratinocyte growth factor-2 on trinitrobenzene sulfonic acid-induced rat model of Crohn's disease
Wang et al. 2016a Am J Transl Res. 8(2):530-43

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7/1/2026

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FGF10 - Wikipedia