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Exposure to antibiotics early in life is particularly critical as it affects the maturation of gut microbiota and may have long-term metabolic effects (7). Antibiotic exposures early in life disrupt the maturation of the gut microbiota and adversely affect children's health. In addition, Antibiotics (J01) increase the frequency of resistant bacteria and accumulate the resistome - the compendium of antibiotic resistance genes - within the gut microbiota (8).
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