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Previous studies suggest that interleukin-17A (IL-17A) plays a crucial role in mediating the interactions between gut microbiota and systemic metabolic functions. Signaling through the intestinal interleukin-17 receptor A (IL-17RA) improves systemic metabolic functions (glucose metabolism, hormone/adipokine levels, visceral adiposity, hepatic lipid deposition), particularly in response to a prolonged high-fat diet. Changes in microbiota composition driven by [Interleukin 17 receptor A (IL-17RA)](brain://oasgYlFtRUaMxRDVQYn3HA/Interleukin17Rece…