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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Cancer / Tumors & Cyclooxygenase-2 (COX-2)

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Cancer cell-intrinsic Cyclooxygenase-2 (COX-2) activity attracts neutrophils and hinders early intratumoral NK cell buildup across several cancer models.
Bonavita et al. 2020…

References (Sources)

Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade
Bonavita et al. 2020
Targeting COX-2 expression by natural compounds: a promising alternative strategy to synthetic COX-2 inhibitors for cancer chemoprevention and therapy
Cerella et al. 2010
Review
The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment.
Greenhough et al. 2009
Review

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7/1/2026

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Cancer / Tumors & Cyclooxygenase-2 (COX-2)

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