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Primary mediastinal large B-cell lymphoma (PMBL) is a rare subtype of lymphoma that is clinically and biologically distinct from Large B-cell lymphoma (LBCL) / Diffuse Large B-Cell Lymphoma (DLBCL) . It also shares overlapping features with classical Hodgkin lymphoma (cHL).
Primary mediastinal B-cell lymphoma (PMBL) is a rare but aggressive non-Hodgkin lymphoma with poor prognoses in relapsed/refractory (R/R) disease. PMBCL shows high programmed cell death-1 ligand expression and variable expression of…