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Acotiamide is a prokinetic, currently approved for use in Japan and India for FD.
Acotiamide is a recently developed Cholinesterase inhibitor that also exerts a presynaptic muscarinic autoreceptor inhibitory activity. It was shown to enhance both contractile and accommodation activities of the stomach and, interestingly, to improve dyspeptic symptoms suggestive of gastroparesis, but not epigastric pain and burning symptoms
Ma…