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Establishment of mutagenesis based reference database might be useful to estimate functional significance of unknown variants in Signal transducer and activator of transcription 1 (STAT1)
The co-existence of loss-of-function and gain-of-function mutations reflects the importance of fine-tuning of Signal transducer and activator of transcription 1 (STAT1) in host immunity
see also:
STAT1 immunity…