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A total of 11 studies with 976 patients were included in this meta-analysis. High levels of sPD-L1 were associated with poor overall and progression-free survival (HR: 2.65, 95% CI: 2.32–3.02; p < 0.001 vs HR: 2.02, 95% CI: 1.24–3.29; p = 0.005). sPD-L1 level was not significantly correlated with sex, smoking status, age, Eastern Cooperative Oncology Group performance status, subtype or EGFR mutation.
Wang & He 2022 Immunotherapy 14(12): 945-956…