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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Breast cancer / Mammacarcinoma (HR+ Her2-) & Drugs/Treatments

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Endocrine therapy (ET) is a standard first-line treatment for advanced Breast cancer / Mammacarcinoma (HR+ Her2-) (ABC). Cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) have demonstrated significantly improved progression-free survival (PFS) with ET in patients with ABC.
Neven et al. 2021 Expert Review of Anticancer Therapy 21: 93-106

see also:
Breast Cancer / Mammacarcinoma & Drugs/Treatments
Breast Cancer / Mammacarcinoma (HR+) (ER+) (Her2-) & Drugs/Treatments
[Fulvestrant + Ribociclib & Breast cancer / Mammacarcinom…

References (Sources)

CDK4/6 inhibitor treatment for patients with hormone receptor-positive, HER2-negative, advanced or metastatic breast cancer: a US Food and Drug Administration pooled analysis
Gao et al. 2020a Lancet Oncology 21: 250-260
Endocrine Treatment and Targeted Therapy for Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Metastatic Breast Cancer: ASCO Guideline Update
Burstein et al. 2021 J Clin Oncol 39: 3959-3977
How we treat HR-positive, HER2-negative early breast cancer
Lopez-Tarruella et al. 2022 Future Oncology 18: 1003-1022
Review
Ribociclib plus fulvestrant in the treatment of breast cancer
Neven et al. 2021 Expert Review of Anticancer Therapy 21: 93-106

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