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The Bacteroidetes phylum is associated with poorer odds of Immune Checkpoint Inhibitors (ICIs) efficacy. Still, for unclear reasons, two of its members, Bacteroides thetaiotaomicron and Bacteroides fragilis, mark possible significant exceptions to the rule
Gopalakrishnan et al. 2018
Repleting Bacteroides fragilis and B. cepacia improved CTLA-4 Immune Checkpoint Inhibitors (ICIs) efficacy in germ-free animal models and simultaneously reduced the risk of…