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RNA Polymerase (RNAP) mutations can also contribute to resistance to Beta-lactam antibiotics. These antibiotics block cell-wall production
According to the WHO, bacterial antimicrobial resistance (AMR) is a critical global public health challenge.
Early clinical successes have been achieved with glycomimetics and vaccines for the treatment and prevention of AMR-related infections.
Fares et al. 2025 Trends in Microbi…