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Members of the NFKB play a crucial balancing act by maintaining tolerance towards the endogenous symbionts, hence establishing homeostasis while activating inflammatory pathways in response to abnormal changes in the microbiome, “dysbiosis” or pathogenic invasion.
The stimulation of NFKB by microbial signatures follows via TLRs, NLRs, and RLRs.
It suggests [NFKB](brain://M0NdA3qVLEmZkzU6DfbFgw/NfKappaBNfk…