Inflammatory Bowel Disease (IBD) & T helper 17 cell (Th17)

T helper 17 cell (Th17) are heavily involved in the pathogenesis of Inflammatory Bowel Disease (IBD)
Strober et al. 2002 Annu Rev Immunol. 20: 495-549
Duerr et al. 2006 Science 314: 1461-1463
Jostins et al. 2012 Nature 491: 119-124
Huang et al. 2017 Nature 547: 173-178

T helper 17 cell (Th17) have been linked to Inflammatory Bowel Disease (IBD) since their discovery in 2005.
Kempski et al. 2017

When mucosal damage occurs, a combination of cytokines, such as Interleukin-6 (IL-6), Transforming growth factor beta (TGF-beta), and Interleukin-1 (IL-1) beta (IL-1F2), induces these cells.
Kempski et al. 2017

see also:
Inflammatory Bowel Disease (IBD) & T helper 17 cell (Th17)

Th17 cells have been associated with immune-mediated diseases, such as IBD, since their discovery in 2005.
Kempski et al. 2017

see also:
Inflammation / Inflammatory Diseases & T helper 17 cell (Th17)