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Preclinical studies have shown that a ketogenic diet (KD) can have beneficial effects in patients with Glioblastoma multiforme (GBM) / Glioblastoma; however, the underlying mechanisms are not yet fully understood
Primary glioma stem-like cells (GSCs) from patients and a GSC cell line were cultured in a glucose-restricted medium containing 3-Hydroxybutyrate / beta-Hydroxybutyric acid (BHB) (simulating Classic ketogenic diet (4:1) / Standard ketogenic diet (SKD) treatment).
Ji et al. 2020 In…