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Sphingosine-1-phosphate receptors, particularly Sphingosine-1 phosphate receptor 1 (S1PR1), are emerging as important modulators of pain pathways. Dysregulation of Sphingosine-1 phosphate receptor / Sphingosine-1 phosphate receptor 1 (S1PR1) signaling can lead to persistent neuroinflammation and nociceptive behaviors
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Tissue-Resident Memory T (TRM) Cells