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Medical Research Finder

meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Breast Cancer / Mammacarcinoma & Cancer microbiome / Tumor microbiome

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Protumor role: Intracellular bacteria (e.g., Staphylococcus xylosus) cause cytosolic dsDNA accumulation, triggering cGAS-STING to upregulate Interleukin-17B (IL-17B) in tumor cells; this reprograms neutrophils to a myeloid-derived suppressor cell (MDSC)-like state. Eliminating intracellular bacteria with doxycycline post-surgery reduces recurrence in preclinical models by restoring [antitumor immunity](br…

Distinct microbial signatures associated with different breast cancer types
Banerjee et al. 2018a Front Microbiol 9: 951
Divergent tumor immunity determined by bacteria-cancer cell engagement
Yao et al. 2026 Cell 189: 1748-1767
Local Breast Microbiota: A “New” Player on the Block
Vitorino et al. 2022a Cancers 14: 3811
Review
Microbiome-derived inosine modulates response to checkpoint inhibitor immunotherapy
Mager et al. 2020 Science 369: 1481-1489
The human tumor microbiome is composed of tumor type–specific intracellular bacteria
Nejman et al. 2020 Science 368: 973-980
The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer
Wang et al. 2022 Cell Metab 34: 581-594
The Microbiome of Aseptically Collected Human Breast Tissue in Benign and Malignant Disease
Hieken et al. 2016 Sci Rep 6: 30751

7/1/2026