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Primary Purpose : Treatment
Allocation : Randomized
Interventional Model : Parallel Assignment
Masking : None (Open Label)
Primary outcome measures:
Proportion of patients with distant intracranial failure as determined by magnetic resonance imaging (MRI) assessment
The authors concluded that after local treatment of one to three melanoma brain metastases, adjuvant whole-brain radiotherapy (WBRT) does not provide clinical benefit regarding distant intracranial control, survival, or preservation of performance status.
Hong et al. 2019a JCO 37: 3132–3141…