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The studies underscore the therapeutic promise of Bifidobacterium breve A1 in preventing memory decline and slowing the advancement of Alzheimer's Disease (AD). Nonetheless, its impact on wild-type (WT) mice remains unexplored. This study seeks to ascertain if Bifidobacterium breve A1 offers a beneficial preventive effect on AD-related pathologies in WT mice. In the study, two-month-old C57BL/6J mice were given oral supplements of Bifidobacterium breve A1 for four months. This supplementation reduced AD-like pathologies by lowering soluble Beta-amyloid 42 levels, inh…