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Probiotics have been suggested to improve cognitive impairment and depressive disorder through the gut–brain axis in both patients and experimental animal models. Nevertheless, the positive impact of probiotics on brain functions in healthy older adults is still uncertain (1).
It is a double-blind, randomized, placebo-controlled clinical trial to evaluate Bifidobacterium bifidum BGN4 + Bifidobacterium longum BORI or placebo in sixty-three enrolled healthy elders (…