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Dupilumab is a fully human IgG4 monoclonal antibody that targets the Interleukin-4 (IL-4) receptor alfa subunit that is endogenously bound by the CD4+ Th2 Cells & Cytokines Interleukin-4 (IL-4) and Interleukin-13 (IL-13)
see also:
Interleukin-4 (IL-4) receptor antagonists
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