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It is differentially expressed in the liver and skin, with high constitutive expression in the liver but not in healthy human skin
PGLYRP2 expression is induced in keratinocytes upon exposure to bacteria through the p38 kinase pathway, correlating with the activation of differentiation markers
PGLYRP2 is also expressed constitutively in resting CD4 and CD8 lymphocytes, NK cells, and bone marrow hematopoietic stem cells
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