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Two long non-muscle isoforms, Myosin Light-Chain Kinase 1 (MLCK1) (full-length long MLCK) and Myosin Light-Chain Kinase 2 (MLCK2) (which lacks a single exon), are predominantly expressed in intestinal epithelial cells and play a central role in modulating various cell functions
It is well-established that Myosin Light-Chain Kinase (MLCK) protein level and activity are markedly increased in intestinal tissues obtained from patients…