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Mesothelioma is a rare and aggressive cancer typically associated with asbestos exposure. It primarily affects the lining of the lungs (pleural mesothelioma) but can also occur in the lining of the abdomen (peritoneal mesothelioma) and other organs. It is an aggressive tumor arising from the serous lining of the lungs (pleurae), heart, abdomen, and testes
Treatment attempts have focused on malignant pleural mesothelioma, which accounts for 90% of cases, is often diagnosed at an advanced stage, and is invariably fatal
Janes et al. 2021 N Engl J Med 385: 1207…