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The U.S. Food and Drug Administration (FDA) initially approved risperidone for the treatment of schizophrenia in adults in 1993, marking it as one of the first second-generation Atypical Antipsychotics (AAPs) approved for this indication.
The European Medicines Agency (EMA) has also approved risperidone for schizophrenia. The oral formulation (Risperdal) and the long-acting injectable Risperdal Consta were both authorized in the European Union in 2002, indicated for the tr…