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Bile acids (BAs) promote nutrient uptake and regulate innate as well as adaptive immunity. Bile acids act on the farnesoid X receptor and the G protein-coupled BA receptor 1 (TGR5). Interestingly, BA receptors (BARs) are expressed on immune cells. BAs promote the anti-tumor immune response by activating and recruiting tumoricidal immune cells such as NKT cells. In addition to promoting anti-tumor immunity, they have an anti-infl…