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Branched-chain amino acid aminotransferase 1 (BCAT1) leads to increased transamination of branched-chain amino acids (BCAAs)
BCAT1 = the enzyme catalyzing the first step of exogenous BCAA degradation to the corresponding Branched-chain alfa-keto acids (BCKAs) and glutamate
This reaction requires alfa-ketoglutarate, and are further metabolized in the mitochondria by branched-chain alpha-keto acid dehydrogenase. Leucine yie…