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BCL2 (B-cell lymphoma 2) plays a crucial role in preventing cell death, making them key targets for therapeutic interventions. The expression levels of BCL-2 proteins vary across different cell types, and some cells depend on specific proteins for survival. In the context of cervical cancer, the proteins BCL-XL and MCL-1 are particularly vital for the survival of cancer cells. Studies have shown that targeting both BCL-XL and MCL-1 with BH3-mimetics holds significant promise.
However, [BCL-2 …