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Gut microbes also influence drugs that undergo enterohepatic recycling by reversing host enzyme metabolic processes and increasing exposure to toxic metabolites as exemplified by the chemotherapy agent irinotecan and non-steroidal anti-inflammatory drugs
People have different gut bacteria, which can change how they react to drugs. For instance, not everyone experiences the same side effects from the cancer drug [irinotecan](brain://SMOjIU8MpUC00ksfc5CEgA/Irin…