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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

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NCT02103270 - Peanut protein vs. Oat flour & Peanut Allergy

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Background:

Dietary avoidance is recommended for peanut allergies. Can Palforzia / Peanut allergen powder (Peanut oral immunotherapy (PNOIT)) help? (1)

Study overview:

NCT02103270 - Peanut protein vs. Oat flour & Peanut Allergy (POISED) is a randomized double-blind, placebo-controlled, clinical phase II treatment trial studying peanut protein or oat flour in 120 enrolled subjects between the ages of 7-55 years old with peanut allergy (1)

Primary outcome measures:

Week 117 - Number of participants with no clinical reactivity to peanuts

Results:

After about 2 years of build‑up and 4 g maintenance, 85% of actively treated patients (peanut‑0 arm) could t…

References (Sources)

Sustained outcomes in oral immunotherapy for peanut allergy (POISED study): a large, randomised, double-blind, placebo-controlled, phase 2 study
Chinthrajah et al. 2019 The Lancet 394: 1437-1449

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