XXX - Clostridioides difficile M3 (NTCD-M3 spores) & Clostridioides difficile infection (CDI) (recurrent)

Background:

The spores of nontoxigenic Clostridium difficile (NTCD) strain M3, known as NTCD-M3 spores, offer protection against challenges with toxigenic strains in hamsters. Administering and colonizing these spores in humans may help prevent both primary and recurrent C. difficile infections (CDI) (1)

Study overview:

XXX - Clostridioides difficile M3 (NTCD-M3 spores) & Clostridioides difficile infection (CDI) (recurrent) is a clinical trial studying single or multiple doses of an oral suspension of Clostridioides difficile M3 (NTCD-M3 spores) (10^4 , 10^6 , or 10^8 spores) or placebo in healthy adult subjects 18 to 45 years old or >60 years. Group 4 (>60…