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Tetryzoline is an alfa agonist for alpha-2 receptor and imidazoline receptor I-1 agonist. Mainly due to its alfa-2 agonism it can constrict conjuctival blood vessels of the eye when taken in the form of eye drops. This relieves the redness of the eye caused by minor ocular irritants. To treat allergic conjunctivitis, tetryzoline can be combined in a solution with antazoline.
In an overdose, slow heart rate and low blood pressure are mainly due to imidazoline-1 receptor agonism. Dry mouth and sedating effects are due to alfa-2 agonism
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