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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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ATP-binding cassette sub-family G member 1 (ABCG1)

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ATP-binding cassette sub-family G member 1 (ABCG1) is a membrane transporter that plays a central role in cellular cholesterol and lipid homeostasis, with emerging relevance in cardiometabolic disease, cancer, and neurodegeneration
Hardy et al. 2017 Int J Mol Sci 18(9): 1892
Kotlyarov & Kotlyarova 2025 Biology 14: 8

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References (Sources)

Biological Functions and Clinical Significance of the ABCG1 Transporter
Kotlyarov & Kotlyarova 2025 Biology 14: 8
Review
Combined Deletion of Macrophage ABCA1 and ABCG1 Leads to Massive Lipid Accumulation in Tissue Macrophages and Distinct Atherosclerosis at Relatively Low Plasma Cholesterol Levels
Out et al. 2008 Arter Thromb Vasc Biol 28: 258-264
Critical Role of the Human ATP-Binding Cassette G1 Transporter in Cardiometabolic Diseases
Hardy et al. 2017 Int J Mol Sci 18(9): 1892
Review

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ATP-binding cassette sub-family G member 1 (ABCG1)

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