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NCT03104036 - Fecal Microbiota Transplantation (FMT) vs 5-Aminosalicylic Acid / Mesalazine & Ulcerative Colitis (UC) is a multicenter, open-label, noninferiority trial to evaluate Fecal Microbiota Transplantation (FMT) or 5-Aminosalicylic Acid / Mesalazine in 45 randomized patients with active left-sided Ulcerative Colitis (UC) (Mayo score 4–10) (1).
Clinical remission, with a total Mayo score ≤ 2 at week 12 with no subscore >1 (1).
Twelve FMT (57%) and eight 5-ASA patients achieved the primary study endpoint. FMT noninferiority with 10% margin was confirmed (95%…