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Medical Research Finder

meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Circulating tumor DNA (ctDNA) & Immune checkpoint inhibitors (ICIs)

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Reductions in Circulating tumor DNA (ctDNA) levels have been associated with improved progression-free survival (PFS) and overall survival (OS) in various cancers treated with Immune checkpoint inhibitors (ICIs).

In a pan-cancer analysis of immune checkpoint blockade:

The “molecular response” metric identified long-term responders and adjudicated benefit among patients with initially radiologically stable disease.

Changes in Circulating tumor DNA (ctDNA) may be more dynamic than radiographic changes and could c…

Changes in circulating tumor DNA and outcomes in solid tumors treated with immune checkpoint inhibitors: a systematic review
Al-Showbaki et al. 2023 J Immunother Cancer 11(2): e005854
Review
Prognostic and Predictive Impact of Circulating Tumor DNA in Patients with Advanced Cancers Treated with Immune Checkpoint Blockade
Zhang et al. 2020q
The Role of Circulating Tumor DNA in Advanced Non-Small Cell Lung Cancer Patients Treated With Immune Checkpoint Inhibitors: A Systematic Review and Meta-Analysis
Wang et al. 2021l Front Oncol. 11: 671874
Review

7/1/2026