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CD26 (Dipeptidyl peptidase 4) (DPP4) rapidly degrades incretin hormones such as Glucagon Like Peptide 1 (GLP-1) and Gastric inhibitory polypeptide (GIP) and inactivates them by cleaving their N-terminal dipeptides. This enzymatic cleavage significantly reduces their half-life and biological activity.
CD26 (Dipeptidyl peptidase 4) (DPP4) is an extracellular peptidase whose high expression has been traditionally used as an indicator of immune activation and effector functions in [T cells](brain://q0lGVzmWvliQrpoQf0EFgw/Effector…