Loading…
Please register to continue your trial period!
meRfi Microbiome provides you with up-to-date, evidence-based insights on the gut microbiota and related health topics.
Access our ever-expanding digital library and get personalized answers through our interactive AI chat platform.
Start your free trial and transform your understanding of the gut microbiota today!
In mammals, serotonin (5-HT) is released by multiple subtypes of serotonergic neurons located in the raphe nuclei (1, 2, 3, 4). These serotonergic subtypes have distinct and widespread projections to distant brain regions (5). Recordings from this neuronal population show diverse activity patterns rather than a single uniform response profile (3, 6, 7, 8, 9). These activity patterns have been linked to rewarding stimuli such as food and to higher-order cognitive processes.
The diversity in activity likely reflects that different serotonergic neurons receive different inputs (10, 11, 12, 13). In humans, altered serotonin levels are associated with changes in impulsivity and decision-making (14, 15, 16)
In humans, c…