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In the developing bone marrow Hemopoietic Stem Cells (HSC) niche-forming MSCs share a common origin with sympathetic peripheral neurons and glial cells
Neuronal components in the bone marrow contribute to the Hemopoietic Stem Cells (HSC) niche for hematopoiesis
Norepinephrine signaling controls Granulocyte colony-stimulating factor (G-CSF)-induced osteoblast suppression, bone CXCL12 downregulation, and HSPC mobilization
The [Sympathetic Nervous System]…