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Rubella is an acute illness caused by the rubella virus, characterized by fever and rash. Although it is generally a clinically mild illness, primary rubella virus infection during early pregnancy can lead to Congenital rubella syndrome (CRS), which has severe medical and public health consequences. The World Health Organization (WHO) estimates that approximately 100,000 cases of Congenital rubella syndrome (CRS) occur annually
Rubella virus is transmitted through respiratory droplets and direct contact. Notably, 25–50% of people infected with the rubella virus are asymptomatic
The clinical disease often results in a mild, self-limited illness characterized by:
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