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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Natural killer cells (NK cells) & Viral infections

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Upon viral infection, Natural killer cells (NK cells) cells expressing certain germline-encoded receptors are selected, expanded, and maintained in an adaptive-like manner. These cells are currently thought to differentiate along a common pathway. However, through fate mapping of single NK cells during murine cytomegalovirus (MCMV) infection, two distinct NK cell lineages contributing to adaptive-like responses have been identified

Conventional NK (cNK) Cells: One lineage was equivalent to conventional NK cells.

ILC1-like NK Cells: The other lineage was transcriptionally similar to [type 1 innate lymphoid cells (ILC1s).](brain://w5Vl4PoqUE2E3Y5X…

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Fate mapping of single NK cells identifies a type 1 innate lymphoid-like lineage that bridges innate and adaptive recognition of viral infection
Flommersfeld et al. 2021 Immunity 54: 2288-2304

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7/1/2026

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Natural killer cells (NK cells) & Viral infections

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