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The objective was to determine the effect of iron fortification on gut microbiota and gut inflammation in African children.
Primary outcome measures:
Reduction in anemia, change in cognitive performance
The authors' conclusion was: Anemic African children carry an unfavorable ratio of fecal enterobacteria to bifidobacteria and lactobacilli, which is increased by iron fortification. Thus, iron fortification in this population produces a potentially more pathogenic gut microbiota profile, and this profile is associated with increased gut inflammation
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