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Medical Research Finder

meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Activation / Activators & Inflammasomes

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Inflammasome activation can be caused by ATP and contact allergens, among others.

Defective inflammasome activation leads to loss of epithelial integrity
Zaki et al. 2020 Immunity 32: 379-391

NLRP3 is activated non-transcriptionally by de-ubiquitination
Haneklaus et al. 2013…

Bacterial recognition pathways that lead to inflammasome activation
Storek & Monack 2015 Immunol Rev 265: 112-129
Review
Cryopyrin activates the inﬂammasome in response to toxins and ATP
Mariathasan et al., 2006 Nature 440: 228-232
Inflammasome activation and assembly at a glance
Malik & Kanneganti 2017 J. Cell Sci. 130: 3955–3963
Review
Modulatory mechanisms controlling the NLRP3 inflammasome in inflammation: recent developrnents
Haneklaus et al. 2013
Targeting CD39 in Cancer Reveals an Extracellular ATP- and Inﬂammasome-Driven Tumor Immunity
Li et al. 2019k Cancer Discovery 9: 1754
The IL-1 family: regulators of immunity
Sims & Smith, 2010
Review
The NLRP3 inﬂammasome protects against loss of epithelial integrity and mortality during experimental colitis
Zaki et al. 2020 Immunity 32: 379-391

7/1/2026