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Prucalopride, a selective 5-hydroxytryptamine 4 receptor agonist used in the treatment of constipation, is able to enhance the gastric emptying rate.
5-HT4 receptor agonists like prucalopride have also proven to be effective in the treatment of gastroparesis
Prucalopride significantly reduced GEBT T½ compared to a placebo (P <0.050) as well as GSCI scores of bloating/ distension (P <0.001), nausea/vomiting (P = 0…