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Frontline pharmacotherapy includes small-molecule antiseizure drugs that typically target ion channels and neurotransmitter systems, but these fail in 30% of patients and do not prevent either the development or progression of epilepsy.
About two dozen medications are prescribed for epilepsy
Roughly 30% of Cases Are Classified as Drug Resistant because Even with Treatment, Patients Continue to Suffer Seizures
Despite more than 20 antiepileptic drugs (AEDs) available, seizures are still uncontrolled in one third of patients.
Mula 2018 Expert Opin. Emerging Drugs 23: 243-2…