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Targeting mutant BRAFV600E is a potential treatment option for LCH.
Lonardi et al. 2020 Cancer Immunol Res 8:829
CSF1R and CSF1 expression in LCH and their role in LC migration and differentiation suggest that CSF1R signaling blockade represents a rational approach for the treatment of LCH, including BRAFV600E and wild-type forms of the disease
Lonardi et …