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meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

AuthorsReferences (Sources)

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Lacticaseibacillus paracasei & Ulcerative Colitis (UC)

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Contents

Preclinical Data:

Lacticaseibacillus paracasei demonstrates potential therapeutic and preventive benefits for Ulcerative Colitis (UC). This is supported by preclinical models and studies in mice, highlighting mechanisms such as gut microbiota modulation, immunomodulation, and improved mucosal repair (1, 2, 3)

Multiple mouse studies show that specific strains of Lacticaseibacillus paracasei can alleviate ulcerative colitis (UC) symptoms. Key findings include:

Reduction of inflammatory cytokines and prevention of intestinal inflammation (1, 5)

Restoration of [gut mic…

References (Sources)

Lacticaseibacillus paracasei BNCC345679 revolutionizes DSS-induced colitis and modulates gut microbiota
Ahmad et al. 2024 Front Microbiol 15: 1343891
Lactobacillus paracasei Expressing Porcine Trefoil Factor 3 and Epidermal Growth Factor: A Novel Approach for Superior Mucosal Repair
Yin et al. 2025 Vet Sci 12(4): 365
Lactobacillus paracasei reduces intestinal inflammation in adoptive transfer mouse model of experimental colitis
Oliveira et al. 2011 Clin Dev Immunol 2011: 807483
The effect of a new symbiotic formulation on plasma levels and peripheral blood mononuclear cell expression of some pro-inflammatory cytokines in patients with ulcerative colitis: A pilot study
Federico et al. 2009 Eur Rev Med Pharmacol Sci 13(4): 285-93
The Exopolysaccharide Produced by Lactobacillus paracasei IJH-SONE68 Prevents and Ameliorates Inflammatory Responses in DSS-Induced Ulcerative Colitis
Noda et al. 2021 Microorganisms 9(11): 2243
Therapeutic effects of Lactobacillus paracasei subsp. paracasei NTU 101 powder on dextran sulfate sodium-induced colitis in mice
Chen et al. 2019 J Food Drug Anal 27(1): 83-92

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