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Medical Research Finder

meRfi® Microbiome - The Digital Gut Microbiome Reference (incl. AI Chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

MYC

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MYC = nuclear transcription factor

MYC is one of the most important oncogenes in cancer
Lancho & Herranz 2018 Trends in Cancer 4: 810

MYC overexpression can be achieved through coding: Gene duplications and Somatic mutations
Lancho & Herranz 2018 Trends in Cancer 4: 810

MYC is amplified in neuroblastoma

MYC is a master regulatory factor of cell proliferation
Dang et al. 2009

MYC regulates genes involved in regulation of glucose and glutamine metabolism
Dang et al. 2009

MYC played a key role in DNA replication.
Studzinski et al. 1986
Iguchi-Ariga et al. 1987

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BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc
Delmore et al. 2011
CDK12 Promotes Breast Cancer Progression and Maintains Stemness by Activating c-myc/β-catenin Signaling
Peng et al. 2020 Current Cancer Drug Targets 20: 156-165
MYC-induced cancer cell energy metabolism and therapeutic opportunities
Dang et al. 2009
MYC-y mice: From tumour initiation to therapeutic targeting of endogenous MYC
Morton & Sansom, 2013
Review
Participation of c-myc protein in DNA synthesis of human cells
Studzinski et al. 1986
Possible function of the c-myc product: Promotion of cellular DNA replication
Iguchi-Ariga et al. 1987
The MYC Enhancer-ome: Long-Range Transcriptional Regulation of MYC in Cancer
Lancho & Herranz 2018 Trends in Cancer 4: 810

7/1/2026